The Naïve Human Antibody Library
The Naïve Human Antibody Library leverages the power of the human immune system by using antibody sequences generated in vivo. Sequences of variable heavy chains are taken from the IgM pool of healthy human donors, where the highest diversity of antibody sequences can be found. The heavy chains are recombined with variable light chains in the phage display vector to maximize diversity.
More than ten billion individual combinations of sequences have been generated and have demonstrated that our human antibody library is a reliable source for the identification of novel, medically relevant antibodies against any target. The library has been used by AbCheck since 2010 with proven and robust results.
Mass Humanized Library
The Mass Humanized Library is an important part of the Rabbit Mass Humanization technology. It is specifically cloned for every single project from immunized rabbits using human frameworks. It contains more than ten billion VH/VL immunized pairs combining the power of in vivo immunization with the best of in vitro engineering and in silico computational optimization.